The impact of hospital infection is greatest in the intensive care unit (ICU) and an effective response to the problem relies on the availability of up-to-date, adequate epidemiological data. The EPIC (European Prevalence of Infection in Intensive Care) study was performed on April 29, 1992, and allowed the collection of data from more than 10,000 patients in Western Europe.
EPIC II, the Extended study of Prevalence of Infection in intensive Care, was performed on May 8, 2007. The study represents a major worldwide collaborative initiative, and the data collected will be useful to address a number of fundamental questions.
The first results from the EPIC II study were published in JAMA in 2009 (Vincent JL, Rello J, Marshall J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA 2009; 302:2323-9).